Extreme Sensitivity to Insulin
نویسندگان
چکیده
منابع مشابه
Insulin Response in Relation to Insulin Sensitivity
OBJECTIVE The purpose of this study was to characterize differences in the acute insulin response to glucose (AIR(g)) relative to insulin sensitivity (S(I)) in black and white premenopausal normoglycemic South African women matched for body fatness. RESEARCH DESIGN AND METHODS Cross-sectional analysis including 57 black and white South African women matched for BMI, S(I), AIR(g), and the disp...
متن کاملQualitative abnormalities in insulin binding in a patient with extreme insulin resistance: decreased sensitivity to alterations in temperature and pH.
Cultured lymphocytes transformed by Epstein--Barr virus were employed to study insulin receptors from a patient with extreme insulin resistance associated with the syndrome of leprechaunism. With cultured lymphocytes from normal subjects, insulin binding to its receptor is exquisitely sensitive to changes in temperature and pH. In cells from normal subjects, insulin binding was increased by app...
متن کاملEndogenous insulin and insulin sensitivity
Results There was a significant inverse correlation between forearm blood flow and insulin sensitivity (r="0·67, P=0·03), patients with lesser degrees of insulin sensitivity having the greater forearm blood flows. There was no correlation with the other haemodynamic or neurohumoral parameters. Patients with greater insulin resistance tended to have higher circulating endogenous insulin levels, ...
متن کاملEarly postprandial Insulin secretion: its relation to Insulin sensitivity
Background: Lack of first phase insulin secretion during oral glucose tolerance test [OGTT] in Type 2 Diabetes Mellitus (DM) is attributed to glucose toxicity. Alternatively, the role of insulin resistance in impaired insulin release secondary to lack of glucose entry into β cells may be responsible, but is not examined. Aim: The role of insulin sensitivity in 1 phase insulin secretion was asse...
متن کاملZataria multiflora increases insulin sensitivity and PPARγ gene expression in high fructose fed insulin resistant rats
Objective(s):In insulin resistance, the insulin action in liver, muscles and adipocytes decreases and result in hyperglycemia, dyslipidemia and hyperinsulinemia. In this study we evaluate the effect of Zataria multiflora extract on insulin sensitivity in high fructose fed insulin resistant rats, since this extract was shown antihyperglycemic effect in streptozotocin induced diabetes in rats. ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1954
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4874.1306